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  1. Interfacial heterogeneity is widely explored to reveal molecular mechanisms of force-mediated pathways due to biased tension. However, the influence of cell density,, curvature, and interfacial heterogeneity o...

    Authors: Huayu Fan, Hui Zhao, Yan Hou, Danni Meng, Jizong Jiang, Eon-Bee Lee, Yinzheng Fu, Xiangdong Zhang, Rui Chen and Yongtao Wang
    Citation: Cellular & Molecular Biology Letters 2025 30:10
    Content type: Research Article Published on:

  2. Hakai protein (CBLL1 gene) was identified as an E3 ubiquitin ligase of E-cadherin complex, inducing its ubiquitination and degradation, thus inducing epithelial-to-mesenchymal transition. Most of the knowledge ab...

    Authors: Juan-José Escuder-Rodríguez, Andrea Rodríguez-Alonso, Lía Jove, Macarena Quiroga, Gloria Alfonsín and Angélica Figueroa
    Citation: Cellular & Molecular Biology Letters 2025 30:9
    Content type: Review Published on:

  3. A previous study found that MAF1 homolog, a negative regulator of RNA polymerase III (MAF1), protects the blood–brain barrier (BBB) in sepsis-associated encephalopathy (SAE); however, the related molecular mechan...

    Authors: Xuebiao Wei, Wenqiang Jiang, Zhonghua Wang, Yichen Li, Yuanwen Jing, Yongli Han, Linqiang Huang and Shenglong Chen
    Citation: Cellular & Molecular Biology Letters 2025 30:8
    Content type: Research Article Published on:

  4. The skin is a barrier that protects the human body against environmental factors (physical, including solar radiation, chemicals, and pathogens). The integrity and, consequently, the effective metabolic activi...

    Authors: Michał Biernacki and Elżbieta Skrzydlewska
    Citation: Cellular & Molecular Biology Letters 2025 30:7
    Content type: Review Published on:

  5. Regulation of messenger RNA (mRNA) transport and translation in neurons is essential for dendritic plasticity and learning/memory development. The trafficking of mRNAs along the hippocampal neuron dendrites re...

    Authors: Pritha Majumder, Biswanath Chatterjee, Khadiza Akter, Asmar Ahsan, Su Jie Tan, Chi-Chen Huang, Jen-Fei Chu and Che-Kun James Shen
    Citation: Cellular & Molecular Biology Letters 2025 30:6
    Content type: Research Article Published on:

  6. Glioblastoma multiforme (GBM) is a highly aggressive brain tumor, characterized by its poor prognosis. Glycolipid metabolism is strongly associated with GBM development and malignant behavior. However, the pre...

    Authors: Zheng Cui, Xiaobai Liu, Tiange E, Hongda Lin, Di Wang, Yunhui Liu, Xuelei Ruan, Ping Wang, Libo Liu and Yixue Xue
    Citation: Cellular & Molecular Biology Letters 2025 30:5
    Content type: Research Article Published on:

  7. Proper adhesion of cells to their environment is essential for the normal functioning of single cells and multicellular organisms. To attach to the extracellular matrix (ECM), mammalian cells form integrin adh...

    Authors: Lucija Mijanović, Darija Putar, Lucija Mimica, Sabina Klajn, Vedrana Filić and Igor Weber
    Citation: Cellular & Molecular Biology Letters 2025 30:4
    Content type: Research Article Published on:

  8. Metabolism is error prone. For instance, the reduced forms of the central metabolic cofactors nicotinamide adenine dinucleotide (NADH) and nicotinamide adenine dinucleotide phosphate (NADPH), can be converted ...

    Authors: Adhish S. Walvekar, Marc Warmoes, Dean Cheung, Tim Sikora, Najmesadat Seyedkatouli, Gemma Gomez-Giro, Sebastian Perrone, Lisa Dengler, François Unger, Bruno F. R. Santos, Floriane Gavotto, Xiangyi Dong, Julia Becker-Kettern, Yong-Jun Kwon, Christian Jäger, Jens C. Schwamborn…
    Citation: Cellular & Molecular Biology Letters 2025 30:3
    Content type: Research Article Published on:

  9. Hypoxia-inducible factors (HIFs) are essential transcription factors that orchestrate cellular responses to oxygen deprivation. HIF-1α, as an unstable subunit of HIF-1, is usually hydroxylated by prolyl hydrox...

    Authors: Jiayi Zhang, Mingxuan Yao, Shiting Xia, Fancai Zeng and Qiuyu Liu
    Citation: Cellular & Molecular Biology Letters 2025 30:2
    Content type: Review Published on:

  10. Epigenetic modifications have been proved to play important roles in the spinal degenerative diseases. As a type of noncoding RNA, the microRNA (miRNA) is a vital class of regulatory factor in the epigenetic m...

    Authors: Yongzhao Zhao, Shuai Jiang, Longting Chen, Qian Xiang, Jialiang Lin and Weishi Li
    Citation: Cellular & Molecular Biology Letters 2025 30:1
    Content type: Brief Report Published on:

  12. Disorders of lipid metabolism are critical factors in the progression of chronic lymphocytic leukemia (CLL). However, the characteristics of lipid metabolism and related regulatory mechanisms of CLL remain unc...

    Authors: Liyan Lu, Xinting Hu, Yang Han, Hua Wang, Zheng Tian, Ya Zhang and Xin Wang
    Citation: Cellular & Molecular Biology Letters 2024 29:159
    Content type: Research Article Published on:

  13. Radiotherapy for pelvic malignant tumors inevitably causes intestinal tissue damage. The regeneration of intestinal epithelium after radiation injury relies mainly on crypt fission. However, little is known ab...

    Authors: Jingyang Cheng, Haiyong Wu and Yanmei Cui
    Citation: Cellular & Molecular Biology Letters 2024 29:158
    Content type: Research Article Published on:

  14. Gastric cancer (GC) represents a prevalent malignancy globally, often diagnosed at advanced stages owing to subtle early symptoms, resulting in a poor prognosis. Exosomes are extracellular nano-sized vesicles ...

    Authors: Jiayu Wang, Huan Zhang, Juntao Li, Xiangyu Ni, Wenying Yan, Yueqiu Chen and Tongguo Shi
    Citation: Cellular & Molecular Biology Letters 2024 29:157
    Content type: Mini Review Published on:

  15. Aberrant elongation of proteins can lead to the activation of oncogenic signaling pathways, resulting in the dysregulation of oncogenic signaling pathways. Eukaryotic elongation factor 2 (eEF2) is an essential...

    Authors: Xuechao Jia, Chuntian Huang, Fangfang Liu, Zigang Dong and Kangdong Liu
    Citation: Cellular & Molecular Biology Letters 2024 29:156
    Content type: Mini Review Published on:

  16. Pulmonary hypertension (PH) presents a puzzling sex bias, being more prevalent in women yet often less severe than in men, and the underlying reasons remain unclear. Studies using animal models, and limited cl...

    Authors: Qiang You, Hequn Song, Ziming Zhu, Jinzheng Wang, Ruixin Wang, Mingjia Du, Yingjie Fu, Jinxiang Yuan and Rubin Tan
    Citation: Cellular & Molecular Biology Letters 2024 29:155
    Content type: Mini Review Published on:

  17. Maternal overnutrition, prevalent among women of childbearing age, significantly impacts offspring health throughout their lifetime. While DNA methylation of metabolic-related genes mediates the transmission o...

    Authors: Ling Zhang, Wenyu Zou, Shixuan Zhang, Honghua Wu, Ying Gao, Junqing Zhang and Jia Zheng
    Citation: Cellular & Molecular Biology Letters 2024 29:154
    Content type: Research Article Published on:

  18. Mitochondria are versatile and complex organelles that can continuously communicate and interact with the cellular milieu. Deregulated communication between mitochondria and host cells/organelles has significa...

    Authors: Meng Zhang, Jin Wei, Chang He, Liutao Sui, Chucheng Jiao, Xiaoyan Zhu and Xudong Pan
    Citation: Cellular & Molecular Biology Letters 2024 29:153
    Content type: Review Published on:

  19. Myoblast fusion plays a crucial role in myogenesis. Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) functions as an RNA N6-methyladenosine reader and exerts important roles in various biological pro...

    Authors: Yuxin Huang, Wei Wang, Xinhao Fan, Xiaoqin Liu, Weiwei Liu, Zishuai Wang, Yixing Li, Yalan Yang and Zhonglin Tang
    Citation: Cellular & Molecular Biology Letters 2024 29:152
    Content type: Research Article Published on:

  21. Exercise exerts positive impacts on skeletal muscle health and homeostasis. Emerging evidence suggests that m6A methylation is involved in various physiological processes. However, the impact of exercise on ad...

    Authors: Shujing Feng, Hao Zhou, Xingzuan Lin, Siyuan Zhu, Huifang Chen, Han Zhou, Ru Wang, Peng Wang, Xiexiang Shao and Jianhua Wang
    Citation: Cellular & Molecular Biology Letters 2024 29:150
    Content type: Research Article Published on:

  22. Traumatic injuries to spinal cord lead to severe motor, sensory, and autonomic dysfunction. The accumulation of inhibitory compounds plays a pivotal role in the secondary damage to sparing neural tissue and th...

    Authors: Zuomeng Wu, Tianyu Han, Yixiang Dong, Wang Ying, Huang Fang, Yunlei Liu, Peiwen Song and Cailiang Shen
    Citation: Cellular & Molecular Biology Letters 2024 29:149
    Content type: Research Article Published on:

  23. Vasculopathy underlies diabetic complications, with perivascular adipose tissue (PVAT) playing crucial roles in its development. However, the changes in the cellular composition and function of PVAT, including...

    Authors: Jiaxuan Li, Zhenyu Tian, Tongxue Zhang, Jiajia Jin, Xinjie Zhang, Panpan Xie, Haiyan Lin, Junfei Gu, Yingjie Wu, Xiaowei Wang, Shucui Zhang, Xuefang Yan, Dong Guo, Zhe Wang and Qunye Zhang
    Citation: Cellular & Molecular Biology Letters 2024 29:148
    Content type: Research Article Published on:

  24. Sjögren’s syndrome (SS) is an autoimmune disease with limited effective treatment options. This study aimed to explore the underlying mechanism by which genistein–estrogen receptor alpha (ERα) complex targets ...

    Authors: Tianjiao Mao, Wei Wei, Bo Chen, Yixin Chen, Shuqi Liang, Guiping Chen, Zhuoyuan Liu, Xiaodan Wu, Lihong Wu, Xiaomeng Li, Nobumoto Watanabe, Kevin H. Mayo, Janak L. Pathak and Jiang Li
    Citation: Cellular & Molecular Biology Letters 2024 29:147
    Content type: Research Article Published on:

  25. Sentrin/SUMO-specific protease 3 (SENP3) is essential to regulate protein stability and function in normal and cancer cells. Nevertheless, its role and action mechanisms in prostate cancer (PCa) remain elusive...

    Authors: Zhenlong Shao, Shutong Liu, Wenshuang Sun, Xuefen Zhuang, Shusha Yin, Ji Cheng, Xiaohong Xia, Yuning Liao, Jinbao Liu and Hongbiao Huang
    Citation: Cellular & Molecular Biology Letters 2024 29:146
    Content type: Research Article Published on:

  26. Differentiating dental pulp stem cells (DPSCs) into odontoblasts is a critical process for tooth self-repair and dentine‒pulp engineering strategies in the clinic. However, the mechanism underlying the regulat...

    Authors: Zeying Zhang, Di Yang, Xiaoyuan Yan, Qiujing Qiu, Jiajie Guo and Lihong Qiu
    Citation: Cellular & Molecular Biology Letters 2024 29:145
    Content type: Research Article Published on:

  27. Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer-related death. This research focuses on investigating the impact and underlying molecular mechanisms of ...

    Authors: Haitao Mei, Qingshan Luo, Junyong Weng, Jialing Hao, Jinfeng Cai, Runkai Zhou, Ce Bian, Yingzi Ye, Shengzheng Luo and Yugang Wen
    Citation: Cellular & Molecular Biology Letters 2024 29:144
    Content type: Research Article Published on:

    The Correction to this article has been published in Cellular & Molecular Biology Letters 2025 30:17

  28. Amyloid β42 (Aβ42) plays a decisive role in the pathology of Alzheimer’s disease. The Aβ42 peptide can aggregate into various supramolecular structures, with oligomers being the most toxic form. However, diffe...

    Authors: Alp Yigit Özdemir, Kateřina Hofbauerová, Vladimír Kopecký Jr., Jiří Novotný and Vladimír Rudajev
    Citation: Cellular & Molecular Biology Letters 2024 29:143
    Content type: Research Article Published on:

  29. RNA splicing is a fundamental step of gene expression. While constitutive splicing removes introns and joins exons unbiasedly, alternative splicing (AS) selectively determines the assembly of exons and introns...

    Authors: Hongkun Hu, Jinxin Tang, Hua Wang, Xiaoning Guo, Chao Tu and Zhihong Li
    Citation: Cellular & Molecular Biology Letters 2024 29:142
    Content type: Review Published on:

  30. HBO1, also known as KAT7 or MYST2, is a crucial histone acetyltransferase with diverse cellular functions. It typically forms complexes with protein subunits or cofactors such as MEAF6, ING4, or ING5, and JADE...

    Authors: Zhanhuan Su, Yang Zhang, Jingqiong Tang, Yanhong Zhou and Chen Long
    Citation: Cellular & Molecular Biology Letters 2024 29:141
    Content type: Mini Review Published on:

  31. Circular RNAs (circRNAs) are differentially expressed in various cardiovascular diseases, including myocardial infarction (MI) injury. However, their functional role in necroptosis-induced loss of cardiomyocyt...

    Authors: Yi Jia, Xiaosu Yuan, Luxin Feng, Qingling Xu, Xinyu Fang, Dandan Xiao, Qi Li, Yu Wang, Lin Ye, Peiyan Wang, Xiang Ao and Jianxun Wang
    Citation: Cellular & Molecular Biology Letters 2024 29:140
    Content type: Research Article Published on:

  32. Liver sinusoidal endothelial cells (LSECs) have transcellular pores, called fenestrations, participating in the bidirectional transport between the vascular system and liver parenchyma. Fenestrated LSECs indic...

    Authors: Izabela Czyzynska-Cichon, Jerzy Kotlinowski, Oliwia Blacharczyk, Magdalena Giergiel, Konrad Szymanowski, Sara Metwally, Kamila Wojnar-Lason, Ewelina Dobosz, Joanna Koziel, Malgorzata Lekka, Stefan Chlopicki and Bartlomiej Zapotoczny
    Citation: Cellular & Molecular Biology Letters 2024 29:139
    Content type: Research Article Published on:

  33. Coronavirus disease 2019 (COVID-19) represents the novel respiratory infectious disorder caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is characterized by rapid spread throughout t...

    Authors: Jiufeng Xie, Cui Yuan, Sen Yang, Zhenling Ma, Wenqing Li, Lin Mao, Pengtao Jiao and Wei Liu
    Citation: Cellular & Molecular Biology Letters 2024 29:138
    Content type: Mini Review Published on:

  34. Human Gb3/CD77 synthase (α1,4-galactosyltransferase, P1/Pk synthase, UDP-galactose: β-d-galactosyl-β1-R 4-α-d-galactosyltransferase, EC 2.4.1.228) forms Galα1 → 4Gal structures on glycosphingolipids and glycoprot...

    Authors: Katarzyna Szymczak-Kulus, Marcin Czerwinski and Radoslaw Kaczmarek
    Citation: Cellular & Molecular Biology Letters 2024 29:137
    Content type: Mini Review Published on:

  35. Oral cancer accounts for 2% of cancer-related deaths globally, with over 90% of cases being oral cavity squamous cell carcinomas (OSCCs). Approximately 50% of patients with OSCC succumb to the disease within 5...

    Authors: Xiu-Ya Chan, Kai-Ping Chang, Chia-Yu Yang, Chiao-Rou Liu, Chu-Mi Hung, Chun-Chueh Huang, Hao-Ping Liu and Chih-Ching Wu
    Citation: Cellular & Molecular Biology Letters 2024 29:136
    Content type: Research Article Published on:

  36. MUC1 is a highly glycosylated transmembrane protein with a high molecular weight. It plays a role in lubricating and protecting mucosal epithelium, participates in epithelial cell renewal and differentiation, and...

    Authors: Weipu Mao, Houliang Zhang, Keyi Wang, Jiang Geng and Jianping Wu
    Citation: Cellular & Molecular Biology Letters 2024 29:135
    Content type: Mini Review Published on:

  37. Chronic pain dramatically affects life qualities of the sufferers. It has posed a heavy burden to both patients and the health care system. However, the current treatments for chronic pain are usually insuffic...

    Authors: Kaige Zheng, Muyan Chen, Xingjianyuan Xu, Peiyi Li, Chengyu Yin, Jie Wang and Boyi Liu
    Citation: Cellular & Molecular Biology Letters 2024 29:134
    Content type: Mini Review Published on:

  38. Authors: Guo-wei Tu, Yi Zhang, Jie-fei Ma, Jun-yi Hou, Guang-wei Hao, Ying Su, Jing-chao Luo, Lulu Sheng and Luo Z
    Citation: Cellular & Molecular Biology Letters 2024 29:133
    Content type: Correction Published on:

    The original article was published in Cellular & Molecular Biology Letters 2023 28:24

  39. Transactivation of epidermal growth factor receptors (EGFR) provides intricate control over multiple regulatory cellular processes that merge the diversity of G protein-coupled receptors (GPCRs) with the robus...

    Authors: Dooti Kundu, Xiao Min, Shujie Wang, Lulu Peng, Xinru Tian, Mengling Wang and Kyeong-Man Kim
    Citation: Cellular & Molecular Biology Letters 2024 29:132
    Content type: Research Article Published on:

  40. Ankyrin repeat domain 1 (Ankrd1) is an acute response protein that belongs to the muscle ankyrin repeat protein (MARP) family. Accumulating evidence has revealed that Ankrd1 plays a crucial role in a wide rang...

    Authors: Xusan Xu, Xiaoxia Wang, Yu Li, Riling Chen, Houlang Wen, Yajun Wang and Guoda Ma
    Citation: Cellular & Molecular Biology Letters 2024 29:131
    Content type: Mini Review Published on:

  41. Caspase-8, a renowned cysteine-aspartic protease within its enzyme family, initially garnered attention for its regulatory role in extrinsic apoptosis. With advancing research, a growing body of evidence has s...

    Authors: Wangzheqi Zhang, Chenglong Zhu, Yan Liao, Miao Zhou, Wenyun Xu and Zui Zou
    Citation: Cellular & Molecular Biology Letters 2024 29:130
    Content type: Review Published on:

  42. Lung diseases triggered by endogenous or exogenous factors have become a major concern, with high morbidity and mortality rates, especially after the coronavirus disease 2019 (COVID-19) pandemic. Inflammation ...

    Authors: Ruyuan He, Yifan Zuo, Ke Yi, Bohao Liu, Congkuan Song, Ning Li and Qing Geng
    Citation: Cellular & Molecular Biology Letters 2024 29:129
    Content type: Mini Review Published on:

  43. Acute transplant rejection is a major component of poor prognoses for organ transplantation. Owing to the multiple complex mechanisms involved, new treatments are still under exploration. Endometrial regenerat...

    Authors: Yini Xu, Shaohua Ren, Hongda Wang, Yafei Qin, Tong Liu, Chenglu Sun, Yiyi Xiao, Bo Shao, Jingyi Zhang, Qiang Chen, Pengyu Zhao, Guangmei Yang, Xu Liu and Hao Wang
    Citation: Cellular & Molecular Biology Letters 2024 29:128
    Content type: Research Article Published on:

  44. Circular RNAs (circRNAs) can influence a variety of biological functions and act as a significant role in the progression and recurrence of glioblastoma (GBM). However, few coding circRNAs have been discovered...

    Authors: Cheng Wei, Dazhao Peng, Boyuan Jing, Bo Wang, Zesheng Li, Runze Yu, Shu Zhang, Jinquan Cai, Zhenyu Zhang, Jianning Zhang and Lei Han
    Citation: Cellular & Molecular Biology Letters 2024 29:127
    Content type: Research Article Published on:

  45. Metastasis, the leading cause of renal cell carcinoma (RCC) mortality, involves cancer cells resisting anoikis and invading. Until now, the role of the matrix metalloproteinase (MMP)-related enzyme, A disinteg...

    Authors: Yu-Ching Wen, Yung-Wei Lin, Kuo-Hao Ho, Yi-Chieh Yang, Feng-Ru Lai, Chih-Ying Chu, Ji-Qing Chen, Wei-Jiunn Lee and Ming-Hsien Chien
    Citation: Cellular & Molecular Biology Letters 2024 29:126
    Content type: Research Article Published on:

  46. Patients with tuberous sclerosis complex (TSC) develop renal cysts and/or angiomyolipomas (AMLs) due to inactive mutations of either TSC1 or TSC2 and consequential mTOR hyperactivation. The molecular events betwe...

    Authors: Shuyun Zhao, Shuai Hao, Jiasheng Zhou, Xinran Chen, Tianhua Zhang, Zhaolai Qi, Ting Zhang, Sajid Jalal, Chuanxin Zhai, Lu Yin, Yufei Bo, Hongming Teng, Yue Wang, Dongyan Gao, Hongbing Zhang and Lin Huang
    Citation: Cellular & Molecular Biology Letters 2024 29:125
    Content type: Research Article Published on:

  47. The involvement of tetraspanins in cancer development has been widely implicated. In this study, the function and molecular mechanisms of tetraspanin 3 (TSPAN3) in non-small cell lung cancer (NSCLC) cells were...

    Authors: Yao Zhang, Chenglong Wang, Yitong Xu and Hongbo Su
    Citation: Cellular & Molecular Biology Letters 2024 29:124
    Content type: Research Article Published on:

  48. Loss-of-function mutations of ZBTB24 cause immunodeficiency, centromeric instability, and facial anomalies syndrome 2 (ICF2). ICF2 is a rare autosomal recessive disorder with immunological defects in serum antibo...

    Authors: He Gao, Ying Zhao, Sai Zhao, Xiao-Qiu Dai, Xiao-Yuan Qin, Wei-Long Zheng, Ting-Ting He, Nan Zhang, Can Zhu, Hong-Min Wang, Wen Pan, Xue-Mei Zhu, Xiao-Ming Gao, Jian-Feng Dai, Fang-Yuan Gong and Jun Wang
    Citation: Cellular & Molecular Biology Letters 2024 29:123
    Content type: Research Article Published on:

  49. Zinc finger MIZ-type containing 2 (ZMIZ2) can function as a coactivator and participate in the progression of certain malignant tumors; however, its expression and underlying molecular mechanism in non-small-c...

    Authors: Xueting Gan, Yuheng Feng, Yang Liu, Xuyong Lin, Xinmiao Yu, Xuezhu Rong and Qiang Han
    Citation: Cellular & Molecular Biology Letters 2024 29:122
    Content type: Research Article Published on:

  50. The dysregulation of miRNAs in lung cancer has been extensively documented, with specific miRNAs acting as both tumor suppressors and oncogenes, depending on their target genes. Recent research has unveiled th...

    Authors: Giovanna Carrà, Jessica Petiti, Federico Tolino, Rita Vacca and Francesca Orso
    Citation: Cellular & Molecular Biology Letters 2024 29:121
    Content type: Mini Review Published on:

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    Journal Impact Factor: 9.2
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Cellular & Molecular Biology Letters

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