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Citation: Cellular & Molecular Biology Letters 2007 12:71
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Microarray analysis reveals the role of matrix metalloproteinases in mouse experimental autoimmune myocarditis induced by cardiac myosin peptides
Autoimmune myocarditis develops after the presentation of heart-specific antigens to autoaggressive CD4+ T cells and after inflammation has infiltrated the tissues. To shed light on global changes in the gene exp...
Citation: Cellular & Molecular Biology Letters 2007 12:3 -
Phenol red in the culture medium strongly affects the susceptibility of human MCF-7 cells to roscovitine
Estrogens play an important role in the growth and terminal differentiation of the mammary gland. Prolonged exposure to estrogens seems to predispose women to breast cancer. It recently became evident that not...
Citation: Cellular & Molecular Biology Letters 2007 12:2 -
Increased expression of HSP70 by colon cancer cells is not always associated with access to the dendritic cell cross-presentation pathway
Dendritic cells (DCs) are highly specialized antigen-presenting cells endowed with the unique ability to not only present exogenous antigens upon exposure to MHC II, but also to cross-present these upon exposu...
Citation: Cellular & Molecular Biology Letters 2007 12:1 -
The molecular diversity of different isolates of Beauveria bassiana (Bals.) Vuill. as assessed using intermicrosatellites (ISSRs)
Inter-microsatellite PCR (ISSR-PCR) markers were used to identify and to examine the genetic diversity of eleven Beauveria bassiana isolates with different geographic origins. The variability and the phylogenetic...
Citation: Cellular & Molecular Biology Letters 2006 12:69 -
Tetraploid somatic hybrids of potato (Solanum tuberosum L.) obtained from diploid breeding lines
Intraspecific somatic hybrids between 16 different diploid breeding lines of Solanum tuberosum L. were produced by PEG-induced fusion. Manually selected heterokaryons were cultured in a Millicells-CM using a post...
Citation: Cellular & Molecular Biology Letters 2006 12:68 -
Genetic instability in the RAD51 and BRCA1 regions in breast cancer
Breast cancer is the most prevalent cancer type in women. Accumulating evidence indicates that the fidelity of double-strand break repair in response to DNA damage is an important step in mammary neoplasias. T...
Citation: Cellular & Molecular Biology Letters 2006 12:63 -
Diploid potato (Solanum tuberosum L.) as a model crop to study transgene expression
This paper presents a method of Agrobacterium-mediated transformation for two diploid breeding lines of potato, and gives a detailed analysis of reporter gene expression. In our lab, these lines were also used to...
Citation: Cellular & Molecular Biology Letters 2006 12:64 -
Partial reversal of transformed fusiform phenotype by overexpression of calreticulin
Calreticulin, a Ca2+-storage and chaperone protein of the ER, has also been shown to affect cell adhesiveness. To examine the effects of differential expression of calreticulin on cellular adhesiveness, we used L...
Citation: Cellular & Molecular Biology Letters 2006 12:65 -
N-terminal brain natriuretic propeptide levels correlate with procalcitonin and C-reactive protein levels in septic patients
The aim of this study was to find the relationship between N-terminal brain natriuretic propeptide (NT-proBNP), procalcitonin (PCT) and C-reactive protein (CRP) plasma concentrations in septic patients. This w...
Citation: Cellular & Molecular Biology Letters 2006 12:62 -
The immunoregulatory effects of edeine analogues in mice
The edeines analogs were tested in several in vitro and in vivo assays using the mouse model, with edeine B (peptide W1) and cyclosporine A as reference compounds. The peptides displayed moderate, stimulatory eff...
Citation: Cellular & Molecular Biology Letters 2006 12:61 -
Phylogenetic analyses within three sections of the genus Vicia
The averaged genomic similarities based on multilocus randomly amplified polymorphic DNA (RAPD) were calculated for eight species representing three sections of the genus Vicia: faba, bithynica and narbonensis. T...
Citation: Cellular & Molecular Biology Letters 2006 11:47 -
Schistosoma japonicum: The design and experimental evaluation of a multivalent DNA vaccine
The aim of this study was to construct and evaluate the immunity efficacy of the DNA multivalent vaccine pVIVO2SjFABP-23. The vaccine was constructed and produced as follows. Forty BALB/c mice were divided into f...
Citation: Cellular & Molecular Biology Letters 2006 11:36 -
Differences in the degree of inhibition of NDP reductase by chemical inactivation and by the thermosensitive mutation nrdA101 in Escherichia coli suggest an effect on chromosome segregation
NDP reductase activity can be inhibited either by treatment with hydroxyurea or by incubation of an nrdA ts mutant strain at the non-permissive temperature. Both methods inhibit replicatio...
Citation: Cellular & Molecular Biology Letters 2006 12:60 -
Spectroscopic studies of D-α-tocopherol concentration-induced transformation in egg phosphatidylcholne vesicles
The effects of embedding up to 60 mol% of α-tocopherol (α-Toc) on the morphology and structure of the egg phosphatidylcholine (PC) membrane were studied using spectroscopic techniques. The resulting vesicles w...
Citation: Cellular & Molecular Biology Letters 2006 12:59 -
A proteomic analysis of the effect of mapk pathway activation on l-glutamate-induced neuronal cell death
Oxidative stress has been implicated in the pathogenesis of neuronal degenerative diseases. It is also widely known that oxidative stress induces mitogen-activated protein kinase (MAPK) signaling cascades. In ...
Citation: Cellular & Molecular Biology Letters 2006 12:57 -
Ischemic heart failure enhances endogenous myocardial apelin and APJ receptor expression
Apelin interacts with the APJ receptor to enhance inotropy. In heart failure, apelin-APJ coupling may provide a means of enhancing myocardial function. The alterations in apelin and APJ receptor concentrations...
Citation: Cellular & Molecular Biology Letters 2006 12:58 -
SIRE-1, A putative plant retrovirus is closely related to a legume TY1-copia retrotransposon family
SIRE-1 is a potential soybean retrovirus which has a gene order similar to Ty1-copia retrotransposons but also contains an envelope-like open reading frame (ORF), which is characteristic of retroviruses. PCR and ...
Citation: Cellular & Molecular Biology Letters 2006 12:53 -
Prins and C-PRINS: Promising tools for the physical mapping of the lupin genome
Two molecular cytogenetics methods, PRINS (primed in situ DNA labeling) and C-PRINS (cycling PRINS), were optimized for the physical mapping of several types of DNA sequences on the mitotic chromosomes of the nar...
Citation: Cellular & Molecular Biology Letters 2006 12:56 -
How influenza’s neuraminidase promotes virulence and creates localized lung mucosa immunodeficiency
Neuraminidase (NA) is an enzyme coded for by the genome of influenza critical for its pathogenicity and survival. Three currently accepted roles for this NA in promoting influenza virulence are: 1. NA cleaves ...
Citation: Cellular & Molecular Biology Letters 2006 12:55 -
Genetic diversity of SIRE-1 retroelements in annual and perennial glycine species revealed using SSAP
Sequence Specific Amplification Polymorphisms (SSAP) were used to measure the distribution and structure of SIRE-1 retroelement populations in annual and perennial Glycine species. For SSAP analysis, primers corr...
Citation: Cellular & Molecular Biology Letters 2006 12:54 -
Induction of heme oxygenase-1 and heat shock protein 70 in rat hepatocytes: The role of calcium signaling
Stress response genes including heat shock proteins are induced under a variety of conditions to confer cellular protection. This study investigated the role of calcium signaling in the induction of two stress...
Citation: Cellular & Molecular Biology Letters 2006 12:52 -
Influences of Lovastatin on membrane ion flow and intracellular signaling in breast cancer cells
Lovastatin, an inhibitor of cellular cholesterol synthesis, has an apparent anti-cancer property, but the detailed mechanisms of its anti-cancer effects remain poorly understood. We investigated the molecular ...
Citation: Cellular & Molecular Biology Letters 2006 12:50 -
Higly fusogenic cationic liposomes transiently permeabilize the plasma membrane of HeLa cells
Cationic liposomes can efficiently carry nucleic acids into mammalian cells. This property is tightly connected with their ability to fuse with negatively charged natural membranes (i.e. the plasma membrane an...
Citation: Cellular & Molecular Biology Letters 2006 12:49 -
Decreased protein nitration in macrophages that overexpress indoleamine 2, 3-dioxygenase
The activity of indoleamine 2, 3-dioxygenase (IDO; E.C. 1.13.11.42) catalyzes the oxidative cleavage of tryptophan to form kynurenine. IDO activity consumes superoxide anions; therefore, we postulated that ove...
Citation: Cellular & Molecular Biology Letters 2006 12:48 -
A new method for the preperative and analytical electrophoresis of cells
In this paper, a new method is described for the horizontal electrophoresis of cells on a density cushion under near-isopycnic conditions. When cell sedimentation is minimized, the electrophoresis of red blood...
Citation: Cellular & Molecular Biology Letters 2006 11:46 -
Helicobacter pylori infection can modulate the susceptibility of gastric mucosa cells to MNNG
The pathogenesis of stomach cells can be associated with their susceptibility to exogenous dietary irritants, like nitrosamines such as dimethylnitrosamines (DMNA), and to the effects of non-dietary factors, i...
Citation: Cellular & Molecular Biology Letters 2006 11:45 -
AtGRP7 is involved in the regulation of abscisic acid and stress responses in arabidopsis
The Arabidopsis AtGRP7 gene, encoding a glycine-rich RNA-binding protein, has been shown to be involved in the regulation of a circadian-regulated negative feedback loop. However, little is known about the role o...
Citation: Cellular & Molecular Biology Letters 2006 11:42 -
Osteoblast differentiation of NIH3T3 fibroblasts is associated with changes in the IGF-I/IGFBP expression pattern
Insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBPs) are essential regulators for osteoblast proliferation and differentiation. It has been reported that Dexamethasone (Dex), an active glucocor...
Citation: Cellular & Molecular Biology Letters 2006 11:38 -
A comparative gene-expression analysis of CD34+ hematopoietic stem and progenitor cells grown in static and stirred culture systems
Citation: Cellular & Molecular Biology Letters 2006 11:51 -
Plant dehydrins — Tissue location, structure and function
Dehydrins (DHNs) are part of a large group of highly hydrophilic proteins known as LEA (Late Embryogenesis Abundant). They were originally identified as group II of the LEA proteins. The distinctive feature of...
Citation: Cellular & Molecular Biology Letters 2006 11:44 -
Is a genetic defect in Fkbp6 a common cause of azoospermia in humans?
FK506-binding protein 6 (Fkbp6) is a member of a gene family containing a prolyl isomerase/FK506-binding domain and tetratricopeptide protein-protein interaction domains. Recently, the targeted inactivation of Fk...
Citation: Cellular & Molecular Biology Letters 2006 11:43 -
A comparative gene-expression analysis of CD34+ hematopoietic stem and progenitor cells grown in static and stirred culture systems
Static and stirred culture systems are widely used to expand hematopoietic cells, but differential culture performances are observed between these systems. We hypothesize that these differential culture outcom...
Citation: Cellular & Molecular Biology Letters 2006 11:39 -
Current concepts in apoptosis: The physiological suicide program revisited
Apoptosis, or programmed cell death (PCD), involves a complex network of biochemical pathways that normally ensure a homeostatic balance between cellular proliferation and turnover in nearly all tissues. Apopt...
Citation: Cellular & Molecular Biology Letters 2006 11:41 -
Endoplasmic reticulum stress and apoptosis
Cell death is an essential event in normal life and development, as well as in the pathophysiological processes that lead to disease. It has become clear that each of the main cellular organelles can participa...
Citation: Cellular & Molecular Biology Letters 2006 11:40 -
Emulsions of oil from Adenanthera pavonina L. seeds and their protective effect
In our previous study, we developed very stable formulations of submicron oil-in-water emulsions from Adenanthera pavonina L. (family Leguminosae, subfamily Mimosoideae) seed oil, stabilised with soybean lecithin...
Citation: Cellular & Molecular Biology Letters 2006 11:37 -
Enhanced expression of selenocysteine lyase in acute glomerulonephritis and its regulation by AP-1
Acute glomerulonephritis can lead to chronic glomerulonephritis or resolve without permanent damage to the kidneys. Differential gene expression was studied in a model of acute and chronic glomerulonephritis t...
Citation: Cellular & Molecular Biology Letters 2006 11:35 -
Erk is involved in the differentiation induced by diallyl disulfide in the human gastric cancer cell line MGC803
Diallyl disulfide (DADS) is a major constituent of garlic. Previously, we found that DADS both inhibited proliferation in human gastric cancer cells in vitro and in vivo, and induced G2/M arrest. In this study, w...
Citation: Cellular & Molecular Biology Letters 2006 11:34 -
The bacterial artificial chromosome (BAC) library of the narrow-leafed lupin (Lupinus angustifolius L.)
The narrow-leafed lupin possesses valuable traits for environment-friendly agriculture and for the production of unconventional agricultural products. Despite various genetic and environmental studies, the bre...
Citation: Cellular & Molecular Biology Letters 2006 11:33 -
The atypical pattern of cell death in B16F10 melanoma cells treated with TNP-470
TNP-470 is an acknowledged anti-angiogenic factor, and was studied clinically as an anti-cancer drug. We previously reported on an additional property of this molecule: the intracellular generation of reactive...
Citation: Cellular & Molecular Biology Letters 2006 11:32 -
The effect of auxins (IAA and 4-Cl-IAA) on the redox activity and medium pH of Zea mays L. root segments
Indole-3-acetic acid (IAA) and 4-chloroindole-3-acetic acid (4-Cl-IAA) were tested at different concentrations and times for their capacity to change the redox activity and medium pH of maize root segments. Th...
Citation: Cellular & Molecular Biology Letters 2006 11:31 -
A comparison of the in vitro antimicrobial activity of liposomes containing meropenem and gentamicin
The antimicrobial activity of eight cationic, two neutral and three anionic liposome compositions containing meropenem and gentamicin was tested in vitro in broth and serum medium. The cationic formulations showe...
Citation: Cellular & Molecular Biology Letters 2006 11:30 -
Genotyping of recombinant Pichia pastoris strains
A simplified amplified-fragment length polymorphism (AFLP) method was used to genotype Pichia pastoris strains obtained by transformation of P. pastoris strain GS115 with a single integration vector. A total of 1...
Citation: Cellular & Molecular Biology Letters 2006 11:29 -
Studies on genetic changes in rye samples (Secale cereale L.) maintained in a seed bank
The aim of this study was to identify genetic changes in rye seeds induced by natural ageing during long-term storage and consecutive regeneration cycles under gene bank conditions. Genomic DNA from four rye s...
Citation: Cellular & Molecular Biology Letters 2006 11:28 -
The heterogeneity of ion channels in chromaffin granule membranes
Chromaffin granules are involved in catecholamine synthesis and traffic in the adrenal glands. The transporting membrane proteins of chromaffin granules play an important role in the ion homeostasis of these o...
Citation: Cellular & Molecular Biology Letters 2006 11:27 -
Protein profiling of sickle cell versus control RBC core membrane skeletons by ICAT technology and tandem mass spectrometry
A proteomic approach using a cleavable ICAT reagent and nano-LC ESI tandem mass spectrometry was used to perform protein profiling of core RBC membrane skeleton proteins between sickle cell patients (SS) and c...
Citation: Cellular & Molecular Biology Letters 2006 11:26 -
Camptothecin induces the transit of FasL trimers to the cell surface in apoptotic HEp-2 cells
Fas ligand (L) is a membrane protein from the tumor necrosis factor (TNF) family. It induces apoptosis upon contact with its Fas/CD95/APO1 receptor. Trimerization of FasL on the surface of effector cells is es...
Citation: Cellular & Molecular Biology Letters 2006 11:25 -
Identification of microsatellite markers in the rye genome
The rye genomic library, which consists of DNA fragments in the range of 0.5–1.1 kb, was screened for the presence of tri-and tetranucleotide and compound microsatellites. Of the 1,600,000 clones analysed, 102...
Citation: Cellular & Molecular Biology Letters 2006 11:23 -
Brefeldin a decreases the activity of the general amino acid permease (GAP1) and the more specific systems for L-leucine uptake in Saccharomyces cerevisiae
Brefeldin A is a commonly used antifungal agent that reversibly blocks protein transport from the endoplasmic reticulum to the Golgi complex. In this study, we aimed to characterize L-leucine uptake in Saccharomy...
Citation: Cellular & Molecular Biology Letters 2006 11:20 -
The assessment of DNA from marine organisms via a modified salting-out protocol
We developed a rapid, practical and non-toxic salting-out method for the extraction of DNA from marine organisms, and tested it on two representative species of Porifera and Cnidaria, both living in associatio...
Citation: Cellular & Molecular Biology Letters 2006 11:13
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Citation Impact
Journal Impact Factor: 10.2 (2024)
5-year Journal Impact Factor: 9.4 (2024)
Source Normalized Impact per Paper (SNIP): 1.594 (2024)
SCImago Journal Rank (SJR): 2.458 (2024)Speed
Submission to first editorial decision (median days): 10
Submission to acceptance (median days): 128Usage 2024
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