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  1. The tumor immune microenvironment (TIME) is an important regulator of tumor progression, growth and metastasis. In addition, tumor metastasis is one of the principal obstacles to the treatment of colorectal ca...

    Authors: Wenqi Du, Xin Quan, Chaoqun Wang, Qiuya Song, Jie Mou and Dongsheng Pei
    Citation: Cellular & Molecular Biology Letters 2024 29:19
    Content type: Research Article Published on:

  2. Loss of CFTR-dependent anion and fluid secretion in the ducts of the exocrine pancreas is thought to contribute to the development of pancreatitis, but little is known about the impact of inflammation on ducta...

    Authors: Dora Angyal, Tessa A. Groeneweg, Anny Leung, Max Desain, Kalyan Dulla, Hugo R. de Jonge and Marcel J. C. Bijvelds
    Citation: Cellular & Molecular Biology Letters 2024 29:18
    Content type: Research Article Published on:

  3. Despite notable advancements in the investigation and management of lung adenocarcinoma (LUAD), the mortality rate for individuals afflicted with LUAD remains elevated, and attaining an accurate prognosis is c...

    Authors: Zhe Wang, Jinyou Li, LongFei Wang, Yaowei Liu, Wei Wang, JiaYao Chen, HuiJun Liang, Y. Q. Chen and ShengLong Zhu
    Citation: Cellular & Molecular Biology Letters 2024 29:17
    Content type: Research Article Published on:

  5. The eukaryotic translation initiation protein eIF5A is a highly conserved and essential factor that plays a critical role in different physiological and pathological processes including stress response and can...

    Authors: Rocío Seoane, Tomás Lama-Díaz, Antonia María Romero, Ahmed El Motiam, Arantxa Martínez-Férriz, Santiago Vidal, Yanis H. Bouzaher, María Blanquer, Rocío M. Tolosa, Juan Castillo Mewa, Manuel S. Rodríguez, Adolfo García-Sastre, Dimitris Xirodimas, James D. Sutherland, Rosa Barrio, Paula Alepuz…
    Citation: Cellular & Molecular Biology Letters 2024 29:15
    Content type: Research Article Published on:

  6. Rheumatoid arthritis (RA) is an autoimmune disease involving T and B lymphocytes. Autoantibodies contribute to joint deterioration and worsening symptoms. Adenosine deaminase (ADA), an enzyme in purine metabol...

    Authors: Amira Atta, Maha M. Salem, Karim Samy El-Said and Tarek M. Mohamed
    Citation: Cellular & Molecular Biology Letters 2024 29:14
    Content type: Mini Review Published on:

  7. TRIM proteins are characterized by their conserved N-terminal RING, B-box, and coiled-coil domains. These proteins are efficient regulators of autophagy, apoptosis, and innate immune responses and confer immun...

    Authors: Nuzhat Ahsan, Mohd Shariq, Avadhesha Surolia, Reshmi Raj, Mohammad Firoz Khan and Pramod Kumar
    Citation: Cellular & Molecular Biology Letters 2024 29:13
    Content type: Review Article Published on:

  8. Extrachromosomal circular DNAs (eccDNAs) exist in human blood and somatic cells, and are essential for oncogene plasticity and drug resistance. However, the presence and impact of eccDNAs in type 2 diabetes me...

    Authors: Xiang Kong, Shu-jun Wan, Tian-bing Chen, Lan Jiang, Yu-jie Xing, Ya-ping Bai, Qiang Hua, Xin-ming Yao, Yong-li Zhao, Hong-mei Zhang, De-guo Wang, Qing Su and Kun Lv
    Citation: Cellular & Molecular Biology Letters 2024 29:12
    Content type: Brief Report Published on:

  10. Burn injuries can be associated with prolonged healing, infection, a substantial inflammatory response, extensive scarring, and eventually death. In recent decades, both the mortality rates and long-term survi...

    Authors: Michael Kohlhauser, Alexandru Tuca and Lars-Peter Kamolz
    Citation: Cellular & Molecular Biology Letters 2024 29:10
    Content type: Review Article Published on:

  11. Skeletal muscle development is pivotal for animal growth and health. Recently, long noncoding RNAs (lncRNAs) were found to interact with chromatin through diverse roles. However, little is known about how lncR...

    Authors: Bolin Cai, Manting Ma, Rongshuai Yuan, Zhen Zhou, Jing Zhang, Shaofen Kong, Duo Lin, Ling Lian, Juan Li, Xiquan Zhang and Qinghua Nie
    Citation: Cellular & Molecular Biology Letters 2024 29:9
    Content type: Research Article Published on:

  12. Acute liver failure (ALF) is a life-threatening disease, but its pathogenesis is not fully understood. NETosis is a novel mode of cell death. Although the formation of neutrophil extracellular traps (NETs) has...

    Authors: Yukun Wang, Chunxia Shi, Jin Guo, Danmei Zhang, Yanqiong Zhang, Long Zhang and Zuojiong Gong
    Citation: Cellular & Molecular Biology Letters 2024 29:8
    Content type: Brief Report Published on:

  13. Parkinson’s disease (PD) affects 1% of people over 60, and long-term levodopa treatment can cause side effects. Early diagnosis is of great significance in slowing down the pathological process of PD. Multiple...

    Authors: Junhan Liang, Zhirong Wan, Cheng Qian, Madiha Rasheed, Changling Cao, Jingyan Sun, Xuezhe Wang, Zixuan Chen and Yulin Deng
    Citation: Cellular & Molecular Biology Letters 2024 29:7
    Content type: Research Article Published on:

  14. Protein synthesis via translation is a central process involving several essential proteins called translation factors. Although traditionally described as cellular “housekeepers,” multiple studies have now su...

    Authors: Saket Awadhesbhai Patel, Md. Khurshidul Hassan and Manjusha Dixit
    Citation: Cellular & Molecular Biology Letters 2024 29:6
    Content type: Mini Review Published on:

  15. The abnormality of chromosomal karyotype is one factor causing poor prognosis of lymphoma. In the analysis of abnormal karyotype of lymphoma patients, three smallest overlap regions were found, in which MYCT1 ...

    Authors: Ying Liang, Xin Wei, Peng-Jie Yue, He-Cheng Zhang, Zhen-Ning Li, Xiao-Xue Wang, Yuan-Yuan Sun and Wei-Neng Fu
    Citation: Cellular & Molecular Biology Letters 2024 29:5
    Content type: Research Article Published on:

  17. Circular RNAs are enriched in cardiac tissue and play important roles in the pathogenesis of heart diseases. In this study, we aimed to investigate the regulatory mechanism of a conserved heart-enriched circRN...

    Authors: Xinyu Fang, Xiang Ao, Dandan Xiao, Yu Wang, Yi Jia, Peiyan Wang, Mengyang Li and Jianxun Wang
    Citation: Cellular & Molecular Biology Letters 2024 29:3
    Content type: Research Article Published on:

  18. Neointimal hyperplasia is a pathological vascular remodeling caused by abnormal proliferation and migration of subintimal vascular smooth muscle cells (VSMCs) following intimal injury. There is increasing evid...

    Authors: Qi-Lan Jiang, Jia-Ying Xu, Qing-Ping Yao, Rui Jiang, Qin Xu, Bo-Tao Zhang, Tao Li and Jun Jiang
    Citation: Cellular & Molecular Biology Letters 2024 29:2
    Content type: Research Article Published on:

  20. Pulmonary fibrosis is a growing clinical problem that develops as a result of abnormal wound healing, leading to breathlessness, pulmonary dysfunction and ultimately death. However, therapeutic options for pul...

    Authors: Wenqing Sun, Siyun Zhou, Lan Peng, Yi Liu, Demin Cheng, Yue Wang and Chunhui Ni
    Citation: Cellular & Molecular Biology Letters 2023 28:105
    Content type: Research Article Published on:

  21. Intervertebral disc degeneration (IVDD) is the major cause of low-back pain. Histone deacetylase 9 (HDAC9) was dramatically decreased in the degenerative nucleus pulposus (NP) samples of patients with interver...

    Authors: Ming Lei, Hui Lin, Deyao Shi, Pan Hong, Hui Song, Bomansaan Herman, Zhiwei Liao and Cao Yang
    Citation: Cellular & Molecular Biology Letters 2023 28:104
    Content type: Research Article Published on:

  22. Glioma is the most pervasive intracranial tumor in the central nervous system (CNS), with glioblastoma (GBM) being the most malignant type having a highly heterogeneous cancer cell population. There is a signi...

    Authors: Chunlin Li, Bowen Li, Hui Wang, Linglong Qu, Hui Liu, Chao Weng, Jinming Han and Yuan Li
    Citation: Cellular & Molecular Biology Letters 2023 28:103
    Content type: Mini Review Published on:

  23. Acute respiratory distress syndrome (ARDS) is a disease with high mortality and morbidity. Regulator of G protein signaling protein 6 (RGS6), identified as a tumor suppressor gene, has received increasing atte...

    Authors: Juan Song, Miao Li, Cuicui Chen, Jian Zhou, Linlin Wang, Yu Yan, Jun She, Lin Tong and Yuanlin Song
    Citation: Cellular & Molecular Biology Letters 2023 28:102
    Content type: Research Published on:

  24. The deer antler, a remarkable mammalian appendage, has a growth rate surpassing that of any other known osseous organ. Emerging evidence indicates that circRNA and MAPK1 play critical roles in chondrocytes. Th...

    Authors: Mengmeng Song, Haibo Yao, Zitong Sun, Danyang Chen, Xiwen Xu, Guohui Long, Lei Wu and Wei Hu
    Citation: Cellular & Molecular Biology Letters 2023 28:101
    Content type: Research Article Published on:

  25. Metabolic states greatly influence functioning and differentiation of immune cells. Regulating the metabolism of immune cells can effectively modulate the host immune response. Itaconate, an intermediate metab...

    Authors: Wenchang Yang, Yaxin Wang, Kaixiong Tao and Ruidong Li
    Citation: Cellular & Molecular Biology Letters 2023 28:100
    Content type: Review Article Published on:

  26. This study aims to explore the emerging trends, dynamic development, and research hotspots of clustered regularly interspaced short palindromic repeats (CRISPR) technology associated with extracellular vesicle...

    Authors: Jianjing Lin, Shicheng Jia, Zilu Jiao, Jiayou Chen, Wei Li, Fuyang Cao and Xintao Zhang
    Citation: Cellular & Molecular Biology Letters 2023 28:99
    Content type: Research Article Published on:

  27. Alzheimer’s disease (AD) is a chronic illness marked by increasing cognitive decline and nervous system deterioration. At this time, there is no known medication that will stop the course of Alzheimer’s diseas...

    Authors: Hany E. Marei, Muhammad Umar Aslam Khan and Anwarul Hasan
    Citation: Cellular & Molecular Biology Letters 2023 28:98
    Content type: Review Article Published on:

  28. Arachidonic acid 15-lipoxygenases (ALOX15) play a role in mammalian erythropoiesis but they have also been implicated in inflammatory processes. Seven intact Alox genes have been detected in the mouse reference g...

    Authors: Florian Reisch, Dagmar Heydeck, Marjann Schäfer, Michael Rothe, Jiaxing Yang, Sabine Stehling, Gerhard P. Püschel and Hartmut Kuhn
    Citation: Cellular & Molecular Biology Letters 2023 28:97
    Content type: Brief Report Published on:

  29. PSA is a type of proto-oncogene that is specifically and highly expressed in embryonic and prostate cancer cells, but not expressed in normal prostate tissue cells. The specific expression of prostate-specific an...

    Authors: Yi Yang, Hongbing Mei, Xiaohong Han, Xintao Zhang, Jianli Cheng, Zhongfu Zhang, Han Wang and Haixia Xu
    Citation: Cellular & Molecular Biology Letters 2023 28:96
    Content type: Brief Report Published on:

  30. Long-term exposure of humans to air pollution is associated with an increasing risk of cardiovascular diseases (CVDs). Astaxanthin (AST), a naturally occurring red carotenoid pigment, was proved to have multip...

    Authors: Jingyi Ren, Bowen Yin, Zihao Guo, Xiaoya Sun, Huanting Pei, Rui Wen, Ziyi Wang, Siqi Zhu, Jinshi Zuo, Yadong Zhang and Yuxia Ma
    Citation: Cellular & Molecular Biology Letters 2023 28:95
    Content type: Research Article Published on:

  32. Periostin is an extracellular matrix protein that plays a critical role in cell fate determination and tissue remodeling, but the underlying role and mechanism of periostin in diabetic cardiomyopathy (DCM) are...

    Authors: Qing-Bo Lu, Xiao Fu, Yao Liu, Zi-Chao Wang, Shi-Yi Liu, Yu-Chao Li and Hai-Jian Sun
    Citation: Cellular & Molecular Biology Letters 2023 28:93
    Content type: Research Article Published on:

  33. Hypervirulent Klebsiella pneumoniae (hvKp) infection-induced sepsis-associated acute lung injury (ALI) has emerged as a significant clinical challenge. Increasing evidence suggests that activated inflammatory mac...

    Authors: Yihan Xu, Chunying Zhang, Danni Cai, Rongping Zhu and Yingping Cao
    Citation: Cellular & Molecular Biology Letters 2023 28:92
    Content type: Research Article Published on:

  35. The pulmonary surfactant that lines the air–liquid surface within alveoli is a protein–lipid mixture essential for gas exchange. Surfactant lipids and proteins are synthesized and stored in the lamellar body (...

    Authors: Wenqin Xu, Xiaocui Ma, Qing Wang, Jingjing Ye, Nengqian Wang, Zhenzhen Ye and Tianbing Chen
    Citation: Cellular & Molecular Biology Letters 2023 28:90
    Content type: Research Article Published on:

  36. The unique expression pattern endows oncofetal genes with great value in cancer diagnosis and treatment. However, only a few oncofetal genes are available for clinical use and the underlying mechanisms that dr...

    Authors: Yiqing Zhu, Bang Xiao, Meng Liu, Meiting Chen, Ningqi Xia, Haiyan Guo, Jinfeng Huang, Zhiyong Liu and Fang Wang
    Citation: Cellular & Molecular Biology Letters 2023 28:89
    Content type: Research Published on:

  37. The musculoskeletal system supports the movement of the entire body and provides blood production while acting as an endocrine organ. With aging, the balance of bone homeostasis is disrupted, leading to bone l...

    Authors: Xu He, Wei Hu, Yuanshu Zhang, Mimi Chen, Yicheng Ding, Huilin Yang, Fan He, Qiaoli Gu and Qin Shi
    Citation: Cellular & Molecular Biology Letters 2023 28:88
    Content type: Mini Review Published on:

  38. Mitochondrial transfer regulates intercellular communication, and mitochondria regulate cell metabolism and cell survival. However, the role and mechanism of mitochondrial transfer in Cd-induced nonalcoholic f...

    Authors: Jian Sun, Yan Chen, Tao Wang, Waseem Ali, Yonggang Ma, Yan Yuan, Jianhong Gu, Jianchun Bian, Zongping Liu and Hui Zou
    Citation: Cellular & Molecular Biology Letters 2023 28:87
    Content type: Research Article Published on:

  39. Membrane rafts play a crucial role in the regulation of many important biological processes. Our previous data suggest that specific interactions of flotillins with MPP1 are responsible for membrane raft domai...

    Authors: Magdalena Trybus, Anita Hryniewicz-Jankowska, Karolina Wójtowicz, Tomasz Trombik, Aleksander Czogalla and Aleksander F. Sikorski
    Citation: Cellular & Molecular Biology Letters 2023 28:86
    Content type: Research Published on:

  40. Ubiquitin–proteasome-system-mediated clearance of misfolded proteins is essential for cells to maintain proteostasis and reduce the proteotoxicity caused by these aberrant proteins. When proteasome activity is...

    Authors: Chenliang Zhang, YiChun Duan, Chen Huang and Liping Li
    Citation: Cellular & Molecular Biology Letters 2023 28:85
    Content type: Research Article Published on:

  42. Zinc finger protein X-linked (ZFX) has been shown to promote the growth of tumor cells, including leukemic cells. However, the role of ZFX in the growth and drug response of chronic myeloid leukemia (CML) stem...

    Authors: Xiuyan Zhang, Yu Wang, Jinchang Lu, Lun Xiao, Hui Chen, Quanxue Li, Yuan-Yuan Li, Peng Xu, Changgeng Ruan, Haixia Zhou and Yun Zhao
    Citation: Cellular & Molecular Biology Letters 2023 28:83
    Content type: Research Published on:

  44. Early and prompt reperfusion therapy has markedly improved the survival rates among patients enduring myocardial infarction (MI). Nonetheless, the resulting adverse remodeling and the subsequent onset of heart...

    Authors: Wenjie Zuo, Renhua Sun, Zhenjun Ji and Genshan Ma
    Citation: Cellular & Molecular Biology Letters 2023 28:81
    Content type: Review Published on:

  45. The mitochondrial gene MCCC2, a subunit of the heterodimer of 3-methylcrotonyl-CoA carboxylase, plays a pivotal role in catabolism of leucine and isovaleric acid. The molecular mechanisms and prognostic value ...

    Authors: Wanjun Liu, Si Chen, Wenqing Xie, Qian Wang, Qianxin Luo, Minghan Huang, Minyi Gu, Ping Lan and Daici Chen
    Citation: Cellular & Molecular Biology Letters 2023 28:80
    Content type: Research Published on:

  46. Lupus nephritis (LN) is associated with significant mortality and morbidity, while effective therapeutics and biomarkers are limited since the pathogenesis is complex. This study investigated the roles of the ...

    Authors: Huimeng Qi, Zhaoguo Zheng and Qiang Liu
    Citation: Cellular & Molecular Biology Letters 2023 28:79
    Content type: Research Published on:

  47. N6-methyladenosine (m6A) modification is a dynamic, reversible process and is the most prevalent internal modification of RNA. This modification is regulated by three protein groups: methyltransferases (“writers”...

    Authors: Xiaoyue Zhang, Qiu Peng and Lujuan Wang
    Citation: Cellular & Molecular Biology Letters 2023 28:78
    Content type: Review Letter Published on:

  48. Hepatic fibrosis is a common consequence of chronic liver diseases without approved antifibrotic therapies. Long noncoding RNAs (lncRNAs) play an important role in various pathophysiological processes. However...

    Authors: Xiaohui Han, Beichen Guo, Sicong Zhao, Yehua Li, Jing Zhu, Yifan He, Jiajun Wang, Qingbin Yao, Shuai Shao, Lina Zheng, Zhemin Shi, Tao Han, Wei Hong and Kun Zhang
    Citation: Cellular & Molecular Biology Letters 2023 28:77
    Content type: Research Published on:

  49. During aging and after traumatic injuries, cartilage and bone cells are exposed to various pathophysiologic mediators, including reactive oxygen species (ROS), damage-associated molecular patterns, and proinfl...

    Authors: Jana Riegger, Astrid Schoppa, Leonie Ruths, Melanie Haffner-Luntzer and Anita Ignatius
    Citation: Cellular & Molecular Biology Letters 2023 28:76
    Content type: Review Published on:

  50. Osteoarthritis (OA), a common joint disorder with articular cartilage degradation as the main pathological change, is the major source of pain and disability worldwide. Despite current treatments, the overall ...

    Authors: Zehao Zhang, Sheng Zhao, Zhaofeng Sun, Chuanxing Zhai, Jiang Xia, Caining Wen, Yuge Zhang and Yuanmin Zhang
    Citation: Cellular & Molecular Biology Letters 2023 28:75
    Content type: Review Letter Published on:

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Cellular & Molecular Biology Letters

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