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  1. Drug-induced liver injury (DILI) is gradually becoming a common global problem that causes acute liver failure, especially in acute hepatic damage caused by acetaminophen (APAP). Paeoniflorin (PF) has a wide r...

    Authors: Xinyu Deng, Yubing Li, Yuan Chen, Qichao Hu, Wenwen Zhang, Lisheng Chen, Xiaohua Lu, Jinhao Zeng, Xiao Ma and Thomas Efferth
    Citation: Cellular & Molecular Biology Letters 2024 29:119
    Content type: Research Article Published on:

  2. Vasculogenic mimicry (VM) is a potential cause of resistance to antiangiogenic therapy and is closely related to the malignant progression of tumors. It has been shown that noncoding RNAs play an important rol...

    Authors: Chunyu Zhang, Jiao Hu, Zhi Liu, Hao Deng, Jiatong Xiao, Zhenglin Yi, Yunbo He, Zicheng Xiao, Jinliang Huang, Haisu Liang, Benyi Fan, Zhihua Wang, Jinbo Chen and Xiongbing Zu
    Citation: Cellular & Molecular Biology Letters 2024 29:118
    Content type: Research Article Published on:

  3. PD-L1 expression on cancer cells is an important mechanism of tumor immune escape, and immunotherapy targeting the PD-L1/PD1 interaction is a common treatment option for patients with melanoma. However, many p...

    Authors: Lucia Martinkova, Pavlina Zatloukalova, Martina Kucerikova, Nela Friedlova, Zuzana Tylichova, Filip Zavadil-Kokas, Ted Robert Hupp, Philip John Coates and Borivoj Vojtesek
    Citation: Cellular & Molecular Biology Letters 2024 29:117
    Content type: Brief Report Published on:

  4. Lysosomes are acidic organelles involved in crucial intracellular functions, including the degradation of organelles and protein, membrane repair, phagocytosis, endocytosis, and nutrient sensing. Given these k...

    Authors: Veronica Ferrari, Barbara Tedesco, Marta Cozzi, Marta Chierichetti, Elena Casarotto, Paola Pramaggiore, Laura Cornaggia, Ali Mohamed, Guglielmo Patelli, Margherita Piccolella, Riccardo Cristofani, Valeria Crippa, Mariarita Galbiati, Angelo Poletti and Paola Rusmini
    Citation: Cellular & Molecular Biology Letters 2024 29:116
    Content type: Mini Review Published on:

  5. Localized scleroderma (LoS) is an autoimmune disorder that primarily affects the skin, and is often treated with autologous fat grafting (AFG). Nevertheless, the retention rate of AFG in patients with LoS is t...

    Authors: Xuanyu Liu, Zhujun Li, Hayson Chenyu Wang, Meng Yuan, Jie Chen, Jiuzuo Huang, Nanze Yu, Zhou Zhou and Xiao Long
    Citation: Cellular & Molecular Biology Letters 2024 29:115
    Content type: Research Article Published on:

  6. Stroke is a type of acute brain damage that can lead to a series of serious public health challenges. Demonstrating the molecular mechanism of stroke-related neural cell degeneration could help identify a more...

    Authors: Yuhua Chen, Wei He, Junlin Qiu, Yangyang Luo, Chenlong Jiang, Feng Zhao, Hong Wei, Jiao Meng, Tianlin Long, Xin Zhang, Lingjian Yang, Quanhua Xu, Juning Wang and Chi Zhang
    Citation: Cellular & Molecular Biology Letters 2024 29:114
    Content type: Research Article Published on:

  7. Cuproptosis is a unique copper-dependent form of cell death that is highly correlated with the metabolic state of cells. Triptolide exerts pharmacological activity by altering the regulation of metal ions. Cup...

    Authors: Yanxia Xiao, Jiameng Yin, Pu Liu, Xin Zhang, Yajun Lin and Jun Guo
    Citation: Cellular & Molecular Biology Letters 2024 29:113
    Content type: Research Article Published on:

  8. Breast cancer (BC) ranks as the third most fatal malignant tumor worldwide, with a strong reliance on fatty acid metabolism. CLDN6, a candidate BC suppressor gene, was previously identified as a regulator of f...

    Authors: Qiu Jin, Da Qi, Mingzi Zhang, Huinan Qu, Yuan Dong, Minghao Sun and Chengshi Quan
    Citation: Cellular & Molecular Biology Letters 2024 29:112
    Content type: Research Article Published on:

  9. Colorectal cancer (CRC) is a form of malignancy that exhibits a comparatively elevated occurrence and fatality rate. Given the relatively slower progress in diagnostic and therapeutic approaches for CRC, there...

    Authors: Lei Yang, Jiawen Shi, Mingyang Zhong, Pingping Sun, Xiaojing Zhang, Zhengyi Lian, Hang Yin, Lijun Xu, Guyin He, Haiyan Xu, Han Wu, Ziheng Wang, Kai Miao and Jianfei Huang
    Citation: Cellular & Molecular Biology Letters 2024 29:111
    Content type: Research Article Published on:

  10. Gastric cancer (GC) is a prevalent malignant tumor, and the RNA-binding protein polypyrimidine tract-binding protein 1 (PTBP1) has been identified as a crucial factor in various tumor types. Moreover, abnormal...

    Authors: Shimin Wang, Xiaolin Wang, Changhong Qin, Ce Liang, Wei Li, Ai Ran, Qiang Ma, Xiaojuan Pan, Feifei Yang, Junwu Ren, Bo Huang, Yuying Liu, Yuying Zhang, Haiping Li, Hao Ning, Yan Jiang…
    Citation: Cellular & Molecular Biology Letters 2024 29:110
    Content type: Research Article Published on:

  11. Circular RNAs (circRNAs) have been shown to be involved in tumorigenesis and progression. However, the role of circGLIS3 (hsa_circ_0002874) in prostate cancer (PCa) has yet not been reported.

    Authors: Xiaofeng Cheng, Heng Yang, Yujun Chen, Zhenhao Zeng, Yifu Liu, Xiaochen Zhou, Cheng Zhang, An Xie and Gongxian Wang
    Citation: Cellular & Molecular Biology Letters 2024 29:109
    Content type: Research Article Published on:

  12. Palmitoylation is a type of lipid modification that plays an important role in various aspects of neuronal function. Over the past few decades, several studies have shown that the palmitoylation of synaptic pr...

    Authors: Jiaying Peng, Danchan Liang and Zhonghao Zhang
    Citation: Cellular & Molecular Biology Letters 2024 29:108
    Content type: Mini Review Published on:

  14. The RNA N6-methyladenosine (m6A) modification has become an essential hotspot in epigenetic modulation. Serine–arginine protein kinase 1 (SRPK1) is associated with the pathogenesis of various cancers. However, th...

    Authors: Anqi Wang, Yuanyuan Zeng, Weijie Zhang, Jian Zhao, Lirong Gao, Jianjun Li, Jianjie Zhu, Zeyi Liu and Jian-an Huang
    Citation: Cellular & Molecular Biology Letters 2024 29:106
    Content type: Research Article Published on:

  15. The organism-wide effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral infection are well studied, but little is known about the dynamics of how the infection spreads in time among or ...

    Authors: Domokos Máthé, Gergely Szalay, Levente Cseri, Zoltán Kis, Bernadett Pályi, Gábor Földes, Noémi Kovács, Anna Fülöp, Áron Szepesi, Polett Hajdrik, Attila Csomos, Ákos Zsembery, Kristóf Kádár, Gergely Katona, Zoltán Mucsi, Balázs József Rózsa…
    Citation: Cellular & Molecular Biology Letters 2024 29:105
    Content type: Brief Report Published on:

  16. Frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-TDP), amyotrophic lateral sclerosis (ALS) and limbic-predominant age-related TDP-43 encephalopathy (LATE) are associated with depositi...

    Authors: Tommaso Staderini, Alessandra Bigi, Clément Lagrève, Isabella Marzi, Francesco Bemporad and Fabrizio Chiti
    Citation: Cellular & Molecular Biology Letters 2024 29:104
    Content type: Brief Report Published on:

  17. Extrachromosomal circular DNA (eccDNA), a kind of circular DNA that originates from chromosomes, carries complete gene information, particularly the oncogenic genes. This study aimed to examine the contributio...

    Authors: Wei Jin, Zhenqun Xu, Yan Song and Fangjie Chen
    Citation: Cellular & Molecular Biology Letters 2024 29:103
    Content type: Research Article Published on:

  19. Prostate cancer (PCa) ranks as the second most prevalent cancer in men, with advanced stages posing significant treatment challenges. Given its solid tumor nature, PCa is highly susceptible to hypoxia, a condi...

    Authors: Siyong Peng, Yingbo Guo, Marie Irondelle, Abigail Mazzu, Michel Kahi, Paula Ferreira Montenegro, Frédéric Bost and Nathalie M. Mazure
    Citation: Cellular & Molecular Biology Letters 2024 29:101
    Content type: Research Article Published on:

  20. Osteoporosis is a global health issue characterized by decreased bone mass and microstructural degradation, leading to an increased risk of fractures. This study aims to explore the molecular mechanism by whic...

    Authors: Jiajia Lu, Xiaojian Shi, Qiang Fu, Yaguang Han, Lei Zhu, Zhibin Zhou, Yongchuan Li and Nan Lu
    Citation: Cellular & Molecular Biology Letters 2024 29:100
    Content type: Research Article Published on:

  21. Skeletal muscular atrophy is a complex disease involving a large number of gene expression regulatory networks and various biological processes. Despite extensive research on this topic, its underlying mechani...

    Authors: Wenpeng Liang, Feng Xu, Li Li, Chunlei Peng, Hualin Sun, Jiaying Qiu and Junjie Sun
    Citation: Cellular & Molecular Biology Letters 2024 29:99
    Content type: Review Published on:

  22. Phospholipid Hydroperoxide Gluthatione Peroxidase also called Glutathione Peroxidase 4 is one of the 25 described human selenoproteins. It plays an essential role in eliminating toxic lipid hydroxy peroxides, ...

    Authors: Patrick Auberger, Cécile Favreau, Coline Savy, Arnaud Jacquel and Guillaume Robert
    Citation: Cellular & Molecular Biology Letters 2024 29:98
    Content type: Mini Review Published on:

  23. Pancreatic cancer (PC) is one of the most malignant cancers with highly aggressiveness and poor prognosis. N6-methyladenosine (m6A) have been indicated to be involved in PC development. Glucan Branching Enzyme...

    Authors: Weiwei Jin, Yanru Yao, Yuhan Fu, Xiangxiang Lei, Wen Fu, Qiliang Lu, Xiangmin Tong, Qiuran Xu, Wei Su and Xiaoge Hu
    Citation: Cellular & Molecular Biology Letters 2024 29:97
    Content type: Brief Report Published on:

  25. An increasing number of studies have demonstrated the association of circular RNAs (circRNAs) with the pathological processes of various diseases and their involvement in the onset and progression of multiple ...

    Authors: Shuo Ma, Yanhua Xu, Xinyue Qin, Mei Tao, Xinliang Gu, Lei Shen, Yinhao Chen, Ming Zheng, Shiyi Qin, Guoqiu Wu and Shaoqing Ju
    Citation: Cellular & Molecular Biology Letters 2024 29:95
    Content type: Research Article Published on:

  26. We have previously identified an unsuspected role for GJB3 showing that the deficiency of this connexin protein induces aneuploidy in human and murine cells and accelerates cell transformation as well as tumor...

    Authors: Junnan Liu, Xue Wang, Wencheng Jiang, Anca Azoitei, Tim Eiseler, Markus Eckstein, Arndt Hartmann, Stephan Stilgenbauer, Mohamed Elati, Meike Hohwieler, Alexander Kleger, Axel John, Felix Wezel, Friedemann Zengerling, Christian Bolenz and Cagatay Günes
    Citation: Cellular & Molecular Biology Letters 2024 29:94
    Content type: Brief Report Published on:

  27. Anti-angiogenic therapy has become one of the effective treatment methods for tumors. Long noncoding RNAs (lncRNAs) are emerging as important regulators of tumorigenesis and angiogenesis in EC. However, the un...

    Authors: Hanbo Ma, Fengyun Weng, Xiaowen Tong, Huaifang Li, Yinan Yao and Jiangjing Yuan
    Citation: Cellular & Molecular Biology Letters 2024 29:93
    Content type: Research Article Published on:

  28. Nasopharyngeal carcinoma (NPC), primarily found in the southern region of China, is a malignant tumor known for its highly metastatic characteristics. The high mortality rates caused by the distant metastasis ...

    Authors: Yao Wu, Qunying Jia, Qi Tang, Lin Chen, Hongyu Deng, Yingchun He and Faqing Tang
    Citation: Cellular & Molecular Biology Letters 2024 29:92
    Content type: Research Article Published on:

  30. The membrane-delimited receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), angiotensin-converting enzyme 2 (ACE2), which is expressed in the intestine, collaborates with broad neutral am...

    Authors: Jinze Li, Yingli Yan, Yang Fu, Zhe Chen, Yongjie Yang, Yu Li, Jie Pan, Feiwu Li, Cuifang Zha, Kai Miao, Lukuyu Ben, Muhammad Kashif Saleemi, Yongwen Zhu, Hui Ye, Lin Yang and Wence Wang
    Citation: Cellular & Molecular Biology Letters 2024 29:90
    Content type: Research Article Published on:

  31. CircR-loop, a recently unearthed regulatory mechanism situated at the crossroads of circular RNA and DNA interactions, constitute a subset of R-loop. This circR-loop have emerged as a crucial player in pivotal...

    Authors: Xinming Su, Yaojie Feng, Ruixiu Chen and Shiwei Duan
    Citation: Cellular & Molecular Biology Letters 2024 29:89
    Content type: Mini Review Published on:

  32. Osteoarthritis (OA) is the most common degenerative joint disorder that causes disability in aged individuals, caused by functional and structural alterations of the knee joint. To investigate whether metaboli...

    Authors: Rong He, Yuchi Wei, Zeyu Peng, Jie Yang, Zhenwei Zhou, Ailin Li, Yongji Wu, Mingyue Wang, Xiangyan Li, Daqing Zhao, Zhonghua Liu, Haisi Dong and Xiangyang Leng
    Citation: Cellular & Molecular Biology Letters 2024 29:88
    Content type: Research Article Published on:

  33. Alzheimer’s disease (AD) is a progressive neurodegenerative disease and apolipoprotein E (APOE) genotypes (APOE2, APOE3, and APOE4) show different AD susceptibility. Previous studies indicated that individuals...

    Authors: Zhiyuan Ning, Ying Liu, Mengyao Wan, You Zuo, Siqi Chen, Zhongshan Shi, Yongteng Xu, Honghong Li, Ho Ko, Jing Zhang, Songhua Xiao, Daji Guo and Yamei Tang
    Citation: Cellular & Molecular Biology Letters 2024 29:87
    Content type: Research Article Published on:

  36. Canine mammary tumors (CMTs) in intact female dogs provide a natural model for investigating metastatic human cancers. Our prior research identified elevated expression of Anterior Gradient 2 (AGR2), a protein...

    Authors: Stephen Hsien-Chi Yuan, Chih-Ching Wu, Yu-Chih Wang, Xiu-Ya Chan, Hao-Wei Chu, Youngsen Yang and Hao-Ping Liu
    Citation: Cellular & Molecular Biology Letters 2024 29:84
    Content type: Research Article Published on:

  37. Senecavirus A (SVA) caused porcine idiopathic vesicular disease (PIVD) showing worldwide spread with economic losses in swine industry. Although some progress has been made on host factors regulating the repli...

    Authors: Huizi Li, Tingting Zheng, Ming Chen, Xiaoling Lei, Shuo Li, Xijiao Chen, Shishi Wang and Zhangyong Ning
    Citation: Cellular & Molecular Biology Letters 2024 29:83
    Content type: Brief Report Published on:

  38. Hepatic stellate cells (HSCs) play a crucial role in the development of fibrosis in non-alcoholic fatty liver disease (NAFLD). Small extracellular vesicles (sEV) act as mediators for intercellular information ...

    Authors: Shihui Li, Fuji Yang, Fang Cheng, Ling Zhu and Yongmin Yan
    Citation: Cellular & Molecular Biology Letters 2024 29:82
    Content type: Research Article Published on:

  39. Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Studies have indicated that immune dysfunction plays a central role in the pathogenesis of sepsis. D...

    Authors: Li-yu Zheng, Yu Duan, Peng-yi He, Meng-yao Wu, Shu-ting Wei, Xiao-hui Du, Ren-qi Yao and Yong-ming Yao
    Citation: Cellular & Molecular Biology Letters 2024 29:81
    Content type: Mini Review Published on:

  40. Sodium-glucose transporter 2 (SGLT2) inhibitors (iSGLT2) are approved medications for type 2 diabetes. Recent studies indicate that iSGLT2 inhibit the growth of some cancer cells. However, the mechanism(s) rem...

    Authors: Camilla Anastasio, Isabella Donisi, Vitale Del Vecchio, Antonino Colloca, Luigi Mele, Celestino Sardu, Raffaele Marfella, Maria Luisa Balestrieri and Nunzia D’Onofrio
    Citation: Cellular & Molecular Biology Letters 2024 29:80
    Content type: Research Article Published on:

  41. Postoperative cognitive dysfunction (POCD) is a common complication after anesthesia/surgery, especially among elderly patients, and poses a significant threat to their postoperative quality of life and overal...

    Authors: Wei-Feng Wu, Chen Chen, Jia-Tao Lin, Xin-Hao Jiao, Wei Dong, Jie Wan, Qiang Liu, Yong-Kang Qiu, Ao Sun, Yi-Qi Liu, Chun-Hui Jin, He Huang, Hui Zheng, Cheng-Hua Zhou and Yu-Qing Wu
    Citation: Cellular & Molecular Biology Letters 2024 29:79
    Content type: Research Article Published on:

  42. Alternative splicing of pre-mRNAs is a fundamental step in RNA processing required for gene expression in most metazoans. Serine and arginine-rich proteins (SR proteins) comprise a family of multifunctional pr...

    Authors: Mingrong Bei and Jianzhen Xu
    Citation: Cellular & Molecular Biology Letters 2024 29:78
    Content type: Mini Review Published on:

  43. Tumor-associated macrophages (TAMs) significantly influence the progression, metastasis, and recurrence of esophageal squamous cell carcinoma (ESCC). The aberrant expression of long noncoding RNAs (lncRNAs) in...

    Authors: Lijun Zhao, Gengchao Wang, Haonan Qi, Lili Yu, Huilong Yin, Ruili Sun, Hongfei Wang, Xiaofei Zhu and Angang Yang
    Citation: Cellular & Molecular Biology Letters 2024 29:77
    Content type: Research Article Published on:

  44. The role of the scavenger receptor CD36 in cell metabolism and the immune response has been investigated mainly in macrophages, dendritic cells, and T cells. However, its involvement in B cells has not been co...

    Authors: Chenfei He, Guoying Hua, Yong Liu and Shuijie Li
    Citation: Cellular & Molecular Biology Letters 2024 29:76
    Content type: Brief Report Published on:

  45. Mechanical spinal cord injury (SCI) is a deteriorative neurological disorder, causing secondary neuroinflammation and neuropathy. ADAM8 is thought to be an extracellular metalloproteinase, which regulates prot...

    Authors: Zhanyang Qian, Rulin Li, Tianyu Zhao, Kunxin Xie, PengFei Li, Guangshen Li, Na Shen, Jiamin Gong, Xin Hong, Lei Yang and Haijun Li
    Citation: Cellular & Molecular Biology Letters 2024 29:75
    Content type: Research Article Published on:

  46. By analyzing a mouse Interspecific Recombinant Congenic Strain (IRCS), we previously identified a quantitative trait locus (QTL), called Mafq1 on mouse chromosome 1, that is associated with male hypofertility and...

    Authors: Sophie Dupuis, Marie-Sophie Girault, Morgane Le Beulze, Côme Ialy-Radio, Luis Bermúdez-Guzmán, Ahmed Ziyyat and Sandrine Barbaux
    Citation: Cellular & Molecular Biology Letters 2024 29:74
    Content type: Research Article Published on:

  47. Reproductive cancers are malignancies that develop in the reproductive organs. One of the leading cancers affecting the male reproductive system on a global scale is prostate cancer (PCa). The negative consequ...

    Authors: Amin Ullah, Wang Jiao and Bairong Shen
    Citation: Cellular & Molecular Biology Letters 2024 29:73
    Content type: Review Published on:

  48. Aberrant mitochondrial fission, a critical pathological event underlying myocardial ischemia/reperfusion (MI/R) injury, has emerged as a potential therapeutic target. The long non-coding RNA (lncRNA) Oip5-as1 ...

    Authors: Xiaowei Niu, Jingjing Zhang, Shuwen Hu, Wenhui Dang, Kaiwen Wang and Ming Bai
    Citation: Cellular & Molecular Biology Letters 2024 29:72
    Content type: Research Article Published on:

  49. Genetic abnormalities in the FGFR signalling occur in 40% of breast cancer (BCa) patients resistant to anti-ER therapy, which emphasizes the potential of FGFR-targeting strategies. Recent findings indicate tha...

    Authors: Monika Gorska-Arcisz, Marta Popeda, Marcin Braun, Dominika Piasecka, Joanna I. Nowak, Kamila Kitowska, Grzegorz Stasilojc, Marcin Okroj, Hanna M. Romanska and Rafal Sadej
    Citation: Cellular & Molecular Biology Letters 2024 29:71
    Content type: Research Article Published on:

  50. Mycobacterium tuberculosis heat-resistant antigen (Mtb-HAg) is a peptide antigen released from the mycobacterial cytoplasm into the supernatant of Mycobacterium tuberculosis (Mtb) attenuated H37Ra strain after au...

    Authors: Jing Wei, Fangzheng Guo, Yamin Song, Tong Feng, Ying Wang, Kun Xu, Jianhan Song, Eldana Kaysar, Reyima Abdukayyum, Feiyang Lin, Kangsheng Li, Baiqing Li, Zhongqing Qian, Xiaojing Wang, Hongtao Wang and Tao Xu
    Citation: Cellular & Molecular Biology Letters 2024 29:70
    Content type: Research Article Published on:

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Cellular & Molecular Biology Letters

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