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Fig. 1 | Cellular & Molecular Biology Letters

Fig. 1

From: YY1 induced USP13 transcriptional activation drives the malignant progression of hepatocellular carcinoma by deubiquitinating WWP1

Fig. 1

USP13 is highly expressed in HCC and predicts poor prognosis. A USP13 mRNA expression levels in different tumor tissues and normal tissues from the GEO and the TCGA databases were analyzed with Xena (http://xena.ucsc.edu/). The blue bars represent normal tissues and red bars represent tumor tissues. B USP13 mRNA levels in HCC and normal liver tissue was analyzed based on TCGA. C USP13 mRNA levels in HCC and normal liver tissue was analyzed based on the GEO (GSE54236) database. D Representative IHC staining images of USP13 in HCC and adjacent tissues. E Quantitative analysis of IHC staining results by ImageJ. F–H Prognostic information including overall survival (OS), disease-specific survival (DSS), and progression-free interval (PFI) were analyzed in the TCGA database. I USP13 mRNA levels in different HCC cell lines. J, K USP13 protein levels in different HCC cell lines, and quantified by ImageJ. Scale bars: 50 µm

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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