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Table 1 Comparison of skeletal muscle mass and function in old and young rats

From: Cdkn1a silencing restores myoblast differentiation by inducing selective apoptosis in senescent cells

Variables

Young

Old

p-Value

Body weight (g)

477.40 ± 35.80

757.32 ± 91.44

 < 0.001

Soleus/body weight (g/g)

0.38 ± 0.03

0.46 ± 0.04

 < 0.001

Gastrocnemius/body weight (g/g)

4.56 ± 0.38

3.24 ± 0.31

 < 0.001

Maximal forelimb strength (g/body weight)

2.40 ± 0.45

1.40 ± 0.30

 < 0.001

Fatigue index (%)

10.90 ± 2.45

35.81 ± 6.74

0.007