Fig. 4
From: A novel mechanism for A-to-I RNA-edited CYP1A1 in promoting cancer progression in NSCLC
CYP1A1 overediting promotes the growth of NSCLC cells in vivo. A, B Images of xenograft tumors after injection of A549 cells or A549I462V cells (n = 5 per group). C The volumes of subcutaneous tumors were recorded once a week for four consecutive weeks. D The subcutaneous tumor weights were weighed at the endpoint time of the experiment. E The orthotopic tumor growth of lung was monitored weekly by in vivo bioluminescence imaging (n = 5 per group). F The bioluminescence signals of orthotopic tumors were measured by mean photon counts. G Gross appearance of orthotopic tumor after lung parenchyma at the left lateral dorsal axillary line injection with A549 cells or A549I462V cells (n = 5 per group)