Fig. 3
From: A novel mechanism for A-to-I RNA-edited CYP1A1 in promoting cancer progression in NSCLC
CYP1A1 A-to-I RNA editing confers enhanced tumorigenicity. A The growth rates of the indicated stable cell lines was measured by CCK-8. OD, optical density. EdU assays revealed that CYP1A1 A-to-I RNA editing enhanced the proliferation ability of indicated A549 (B) and H1299 (C) cells. Scale bars: 330 μm. The invasion (D, E) and migration abilities (F, G) of indicated stable cell lines were enhanced by CYP1A1 A-to-I RNA editing through Transwell assays. Scale bars: 220 μm. Scale bars: 220 μm. Standard deviation (SD) of three independent experiments. One-way ANOVA with Tukey’s test as post hoc test was used to assess the difference; *p < 0.05; **p < 0.01; ***p < 0.001