Fig. 2

hUC-MSC transplantation improves lupus nephritis in MRL/lpr mice at week 22. A Line plot of 24-h urinary protein levels in MRL/lpr mice from weeks 6 to 20. B Plasma creatinine levels in MRL/lpr mice at week 22. C BUN levels in MRL/lpr mice at week 22. D Representative images of renal pathological staining (H&E and Masson) across all groups at week 22 (scale bar = 50 μm). E Glomerulonephritis scores of renal lesions. F Quantitative analysis of renal fibrosis (% blue staining). G Representative images of renal immunofluorescence deposition of IgG and complement C3 in all groups at week 22 (scale bar = 20 μm). H Quantitative analysis of glomerular C3 deposition. I Quantitative analysis of glomerular IgG deposition. N = 7 per group. *P < 0.05, **P < 0.01