Fig. 2
From: SWI/SNF-type complexes–transcription factor interplay: a key regulatory interaction
Transcriptional control of gene expression involves interaction between the SWI/SNF CRC and transcription factors. A A pioneer transcription factor binds to specific DNA sites and then forms a complex with SWI/SNF to open chromatin. B A pioneer transcription factor recruits SWI/SNF to chromatin and increases chromatin accessibility. C A TF is recruited by SWI/SNF, which promotes SWI/SNF complex-dependent chromatin modeling. D The different modes of action of pioneer TFs, TFs, and general TFs (GTFs) and their interdependence with SWI/SNF chromatin remodeling complexes. E Chromatin remodeling by SWI/SNF-induced nucleosome sliding and TF eviction. F The SWI/SNF complex activates or silences gene expression by controlling access to binding sites for an activator (ABS) or repressor (RBS) of transcription. G The SWI/SNF complex plays an essential role in modulating promotor and enhancer accessibility, required for TF-mediated gene expression activation