Fig. 6

Downregulation of KLF5 delays wound healing in diabetic wound. A Generating a full-thickness skin defect model and treatment protocol. B Representative images of wound healing process in mice in each group. Scale bar = 5 mm. C Schematic diagram of the wound managed by different treatments in 21 days. D The wound closer percentage was evaluated post-wounding. All experiments were performed in triplicate and were repeated three times to confirm the findings (*p < 0.05). Data represent mean ± SD (n = 21 animals per group), *p < 0.05, **p < 0.01 versus control; ^#p < 0.05, ^##p < 0.01 versus DM