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Fig. 6 | Cellular & Molecular Biology Letters

Fig. 6

From: Human urine stem cells protect against cyclophosphamide-induced premature ovarian failure by inhibiting SLC1A4-mediated outflux of intracellular serine in ovarian granulosa cells

Fig. 6

The related genes and signal pathways that have an antiapoptotic role associated with hUSC-Exo were determined in CTX-induced GC-injury models. A, B Venn diagram statistics for up- or downregulated differential genes between the CTX group, CTX + hUSC-Exo group, and CTX + hUSC-Exo group, respectively. C, D Heat map of differential genes was obtained from Venn plot statistics using differential expression ploidy. E Reactome analysis of the differential genes. F GO enrichment analysis of the differential genes. G The expressions of genes causing Th17 cell differentiation were determined using GSEA analysis in the different groups. H KEGG analysis of the differential genes revealed that most of them were enriched in the AKT signaling pathway

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