Fig. 6

The related genes and signal pathways that have an antiapoptotic role associated with hUSC-Exo were determined in CTX-induced GC-injury models. A, B Venn diagram statistics for up- or downregulated differential genes between the CTX group, CTX + hUSC-Exo group, and CTX + hUSC-Exo group, respectively. C, D Heat map of differential genes was obtained from Venn plot statistics using differential expression ploidy. E Reactome analysis of the differential genes. F GO enrichment analysis of the differential genes. G The expressions of genes causing Th17 cell differentiation were determined using GSEA analysis in the different groups. H KEGG analysis of the differential genes revealed that most of them were enriched in the AKT signaling pathway