Fig. 6

hnRNP A1 promotes nuclear export of m6A-modified circCDK14. A and B The hnRNP A1 mRNA (A) and protein (B) expression level after hnRNP A1 overexpression; C and D the hnRNP A1 mRNA (C) and protein (D) expression level after hnRNP A1 interference; E hnRNP A1 antibody for circCDK14 enrichment; F–G hnRNP A1 antibody for circCDK14 enrichment after hnRNP A1 overexpression or interference; H–I m6A antibody for circCDK14 enrichment after hnRNP A1 overexpression or interference; J–K circCDK14 expression in the nucleus and cytoplasm after hnRNP A1 overexpression or interference; L the binding relationship between hnRNP A1 and circCDK14 after SRSF3 interference; M the binding relationship between SRSF3 and circCDK14 after hnRNP A1 interference. The western blot, RIP and MeRIP were repeated 3 times (n = 3) and other experiments were performed in triplicate and repeated 3 times (n = 9)