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Fig. 7 | Cellular & Molecular Biology Letters

Fig. 7

From: Heterogeneous focal adhesion cytoskeleton nanoarchitectures from microengineered interfacial curvature to oversee nuclear remodeling and mechanotransduction of mesenchymal stem cells

Fig. 7

Mechanism of curvature, spreading area and aspect ratio on cytoskeleton distribution and nuclear activity in the engineered cells. a Fluorescent pictures of actin (green) and nuclei (blue) in the engineered cells, scale bar represents 50 μm; b nuclear area of the engineered cells, data are presented as mean ± standard deviation (SD), n = 5, n.s.: no significance, **p < 0.01, ***p < 0.001; c angular compliance of nuclei in the engineered cells; d fluorescent pictures of BrdU positive nuclei, BrdU is shown in green, nuclei in blue, scale bar represents 200 μm; e nuclear activity by calculating BrdU positive cells in the engineered cells, data are presented as mean ± SD, n = 5, n.s.: no significance, *p < 0.05, **p < 0.01, ***p < 0.001

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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