Fig. 3

Elastic modulus of LSEC isolated from control and Mcpip1 KO mice. Nanomechanical properties of LSEC quantified by the elastic modulus calculated for (A) the conical indenter (F = 1.0 nM) and (B) the hemispherical indenter (r = 5.0 µm, F = 2.0 nN). Two time points of 3-month-old and 6-month-old mice were compared. Additionally, the effect of 30 min of cytochalasin B was determined. n = 3–6 animals