Fig. 2
From: Research progress of ankyrin repeat domain 1 protein: an updated review
The cellular roles of Ankrd1 in cardiomyocytes. As a transcriptional regulator, Ankrd1 participates in the regulation of transcriptional activity by interacting with different transcriptional factors (TFs), including YB-1, GATA 4, and p53. The biological functions in cells regulated by Ankrd1 and these TFs are displayed in gray boxes. Ankrd1 is also a structural protein, and contributes to the structural integrity of the sarcomere by interacting with titin, CASQ2, and myopalladin. This figure was improved on the basis of the study by Samaras SE et al. [27]