Fig. 3

SRPK1 is the potential target of METTL3 in LUAD. A Flowchart for screening potential targets of METTL3. B Venn diagram of genes with differential m6A quantity, m6A level, and mRNA expression. C Heatmap of m6A levels of related genes in the microarray. D Bar chart of related genes expression in the TCGA database. E The H1299 cell’s m6A levels of E2F8 were determined by MeRIP–qPCR. F The A549 and H1299 cell’s m6A level of SRPK1 was assessed by MeRIP–qPCR. *P < 0.05; **P < 0.01