Fig. 11
The correlations of relevant molecules in LUAD samples. A The correlation between SRPK1 and METTL3, SRPK1 and hnRNPA1, SRPK1 and PKM in LUAD was analysed by GEPIA. B Western blot analysis of protein levels of METTL3, SRPK1, hnRNPA1, PKM1 and PKM2 in 20 paired LUAD and adjacent tissues. C Relative quantification of protein levels in 20 paired LUAD and adjacent tissues. D The correlation between SRPK1 and METTL3, SRPK1 and hnRNPA1, SRPK1 and PKM1, SRPK1 and PKM2 in 20 paired LUAD tissues. E A diagram showing that METTL3 stabilized SRPK1 levels in an m6A-IGF2BP2-dependent manner and thus promoted glycolysis in LUAD