Fig. 5

Effects of integrin β1 sialylation on the pro-metastatic function of sEV. A Experimental workflow (schematic). B–E Representative photographs and haematoxylin and eosin (H&E) staining of livers or lungs. F, G Flag-tagged WT or Δ7–8 mutant integrin β1 expression in liver (F) or lung (G) by immunohistochemistry. H Distribution of sEV in mice after injection of sEV by tail vein