Fig. 4
From: Uremic toxins mediate kidney diseases: the role of aryl hydrocarbon receptor
The structure of mouse AhR. AhR contains a basic helix-loop-helix (bHLH) domain and two repeats of the Per-Arnt-Sim (PAS) domain, known as PAS-A and PAS-B. The bHLH and PAS-A domains of AhR are responsible for ARNT binding, and the PAS-B domain is responsible for ligand binding. The C-terminal acidic domain of AhR interacts with cullin 4B (CUL4B)