Fig. 10

Overexpression of PFN2 or inhibition of miR-1287-5p reversed NSCLC cell proliferation and migration after silencing circ-SLC16A1. A, B Clone formation showing the proliferation ability in both A549 and H1833 cells. Data shown as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001 versus NC. ^##P < 0.01, ^###P < 0.001 versus sh-circ-SLC16A1. C–E EdU detection showing the proliferation ability in both A549 and H1833 cells. Data shown as mean ± SD. *P < 0.05, ***P < 0.001 versus NC. ^##P < 0.01, ^###P < 0.001 versus sh-circ-SLC16A1. F, G Transwell detection showing invasion and migration of A549 and H1833 cells. Data shown as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001 versus NC. ^##P < 0.01, ^###P < 0.001 versus sh-circ-SLC16A1