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Fig. 11 | Cellular & Molecular Biology Letters

Fig. 11

From: New insights into the role of mitochondrial metabolic dysregulation and immune infiltration in septic cardiomyopathy by integrated bioinformatics analysis and experimental validation

Fig. 11

Metformin improves cardiac function by alleviating mitochondrial injury and inflammatory response in mice with SCM. A–D Results of echocardiography. LVEF, left ventricular ejection fraction; FS, left ventricular fraction shortening; LVDd, left ventricular diastolic dimension; LVDs, left ventricular systolic dimension. E, F Analysis of the mitochondrial membrane potential in isolated cardiomyocytes loaded with JC-1. G–I Comparison of expression of inflammation factors between different groups (N = 6 mice or eight independent cell samples per group). *p < 0.05, **p < 0.01, ***p < 0.001

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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