Fig. 2
From: The regulatory relationship between transcription factor STAT3 and noncoding RNA
STAT3 binds to lncRNA promoters to upregulate their expression, promoting Th17 or M2 macrophage differentiation. In Th17 and M2 macrophages, STAT3 directly binds to the promoters of lncRNAs MIAT and lnc-M2 to upregulate their expression. The lncRNAs promote the differentiation of Th17 and M2 macrophages by upregulating the expression of differentiation-related genes