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Fig. 1 | Cellular & Molecular Biology Letters

Fig. 1

From: IP3R1-mediated MAMs formation contributes to mechanical trauma-induced hepatic injury and the protective effect of melatonin

Fig. 1

Significant increase of MAMs was observed in MT-induced hepatic injury. A Serum ALT levels at different time points. B Serum AST levels at different time points. C Representative TEM images at different time points at × 15,000 magnification. Scale bars: 1 μm. Pictures in bottom side are the magnified ones from top side, indicated by black frame. M: mitochondria; ER: Endoplasmic reticulum; Red arrow: minimum ER-mitochondria distance. D Quantification of the minimum distance between ER and mitochondria. E Quantification of ER length close to mitochondria normalized by total ER length at different time. All of the values are shown as the means ± SEM. n = 8 in each group. *P < 0.05, **P < 0.01 vs Sham; ^^P < 0.01 vs 0 h after MT

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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