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Fig. 4 | Cellular & Molecular Biology Letters

Fig. 4

From: Synthetic CRISPR/dCas9-KRAB system driven by specific PSA promoter suppresses malignant biological behavior of prostate cancer cells through negative feedback inhibition of PSA expression

Fig. 4

PSA promoter-driven CRISPR-dCas9-KRAB suppresses the colony-forming ability and transwell transmembrane migration ability of prostate cancer cells. A The colony formation assay revealed that PSA-dCas9-KRAB significantly inhibited the colony-forming ability of prostate cancer cells. B Transwell assay revealed that PSA-dCas9-KRAB significantly inhibited the migration number of prostate cancer cells. **P < 0.01 (Student’s t-test, n = 3 replicates)

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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