Fig. 4

Time-dependent increase of miR-155-5p load in activated macrophage-derived exosomes. A Expression of inflammation-related miRNAs in iHvKp-exo and control exosomes measured by RT-PCR. B Expression of miR-155-5p in exosomes at different time points after iHvKp stimulation measured by RT-PCR. C The intersection of predicted target genes of miR-155-5p from three databases (Targetscan, miRDB, mirWalk). D KEGG pathway analysis was performed on potential target genes of miR-155-5p. Data are represented as mean ± SEM, *p < 0.05, **p < 0.01, ***p < 0.001, n = 3