Fig. 3

CEBPB is associated with macrophage activation in LN. A Analysis of single-cell expression of CEBPB in the kidney using the Human Protein Atlas database. B Correlation between CEBPB expression and macrophage infiltration in kidney tissues (n = 23) by Pearson’s correlation analysis. C Immunohistochemical detection of CD68 in the kidney tissues of LN mice with CEBPB downregulation. D Immunohistochemical detection of F4/80 in the kidney tissues of LN mice with CEBPB downregulation. E Detection of macrophages in single cell suspensions of mouse kidney tissues by flow cytometry. F The IL-1β, IL-6, and TNF-α levels in mouse serum by ELISA. Data are presented as means ± SD (n = 8, *p < 0.05). Data were statistically analyzed using one-way ANOVA