Fig. 1

The expression of GZMA was inhibited significantly by crRNA/Cas13d. A The plasmid profile and sequences of crRNA were presented. B The GZMA mRNA expression was suppressed dramatically by GZMA crRNA/Cas13d. C The GZMA protein expression was restrained via GZMA crRNA1/Cas13d using ELASA assay. *Means P < 0.05