Fig. 5

Effects of the CRISPR–dCas9–KRAB system on in vivo tumor cell growth compared with the sgRNA control group. A nude mouse tumorigenesis experiment was used to detect the relative cell growth. There were statistical differences between the two groups in MG-63. The P-value was less than 0.01. A Student’s t-test was used for statistics. A Representative pictures of tumors. B Statistical curves. C Statistical histograms