Fig. 6

Examination of mitochondrially related markers in four groups in vitro. A Western blot of mitochondrial fusion-related markers (Drp1, p-Drp1, Mfn1, and Mfn2) in each group. B–D Relative expression of mitochondrial fusion-related markers detected by western blot. *p < 0.05, **p < 0.01, compared with control group; ^#p < 0.05, ^##p < 0.01, compared with cisplatin (Cis) group. E Immunohistochemistry of Mfn2 in each group. F Co-immunoprecipitation assays detecting Drp1 and PGAM5 interaction in HK-2 cells