Fig. 3

Inhibition of miR-15 reduced inflammatory responses induced by CVB3. a through c – The generation of IL-1β (a), IL-6 (b) and IL-18 (c) was determined using ELISA. d through f – The protein expressions of NLRP3, caspase-1 p20 and pro-caspase-1 were determined using western blotting with corresponding histogram analysis, normalizing to GAPDH expression. *p < 0.05 versus the control group, #p < 0.05 versus the CVB3 group