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Fig. 2 | Cellular & Molecular Biology Letters

Fig. 2

From: RETRACTED ARTICLE: MicroRNA-582–3p negatively regulates cell proliferation and cell cycle progression in acute myeloid leukemia by targeting cyclin B2

Fig. 2

Effects of miR-582–3p overexpression on cell proliferation and cell cycle progression in AML cells. THP-1 cells were transfected with miR-582–3p mimics or miR-NC. a The expression of miR-582–3p was determined via quantitative real-time PCR. b CCK8 assay was performed to evaluate cell proliferation at the indicated times following transfection. c Representative images from the colony formation assay (upper) and quantification of colonies (below) with miR-582–3p mimics or miR-NC-transfected THP-1 cells. d THP-1 cells were stained with PI and subjected to flow cytometry analysis, followed by quantification of cell cycle distribution. Data are presented as means ± SD from three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001 vs. miR-NC

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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