Fig. 2
From: The norpurpureine alkaloid from Annona purpurea inhibits human platelet activation in vitro
Norpurpureine is a non-selective inhibitor of human platelet aggregation. Typical traces of platelet aggregation responses monitored by changes in the light transmission signal over time are shown. Platelets were incubated with the vehicle (0.25% DMSO, blue), 250 μM purpureine (black) or 250 μM norpurpureine (red) for 10 min before their stimulation with 10 μM ADP (a), 1 μg/ml collagen (b) (in PRP) or 0.075 U/ml thrombin (c) (in WP). These original tracings are representative of five curves done for each agonist